DNA

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  • 5'
  • 3'
  • Leading Strand
  • Then DNA polymerase binds to the leading strand and 'walks' along it. It acts like Cupid, adding new complementary bases.
  • RNA primer (produced by the enzyme RNA primase) binds to the end of the leading strand. The primer acts as a starting point for DNA synthesis.
  • There are plenty more fish in the sea...
  • 5'
  • 3'
  • DNA polymerase adds new complementary nucleotide bases (A, C, G and T) to the strand of DNA in the 5’ to 3’ direction. This is continuous.
  • But...it's different for the 'lagging strand'. Remember, the lagging strand is oriented in the 5' to 3' direction.
  • 5'
  • 3'
  • Numerous RNA primers are made by the primase enzyme and bind at various points along the lagging strand.
  • I'll have to do this one-by-one, and not continuously... i guess that means 'discontinously'
  • You see, DNA Polymerase adds nucleotides in the 5' to 3' direction.
  • The primers are removed by an enzyme called exonuclease. The gaps are filled with more nucleotides and proofread.
  • That's why it's called called 'semi-conservative replication'
  • Now there are 2 strands, identical to the parent strand (in terms of base-sequence). Oh, and DNA ligase seals seals up the sequence of DNA into two continuous double strands.
  • YES! Thank you so much Boney!
  • Geddit now, kid?
  • Heh. Processes like these make me wish I was alive again. Go ace that test kid.
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