There are three different lines of defense that include non-specific and specific. They protect us and help keep us healthy.#160;
Stomach acid kills harmful bacteria that has been swallowed and breaks it down into strong acids.
First Line of Defense
The First line of defense has mucus and cillia that allows for the cillia to sweep up mucus into the throat as you breath in foreign particles.#160;
Saliva, tears, and sweat contain many chemicals that break down bacteria#160;
The skin is the bodies first line of defense against harmful bacteria entering the body.#160;
When this occurs, capillaries dilate causing the skin to redden and become warm.
Second Line of Defense:Inflammatory Response
A non-specific inflammatory response is used when tissues are damaged by physical or chemical agents or pathogens.
pain receptors are activated during this response that allow for proteins and fluids to escape into affected tissue.
The three lines of defense include the the first and third which are non-specific and the third line of defense that is a specific line of defense.
Second Line of Defense- White Blood Cells
There are different types of white blood cells that are responsible for eating foreign particles or dead body cells. Once engulfed, the phagocytes break them into organelles.
First Line of Defense- This includes the physical and chemical barriers that help to protect the body from infection and prevent pathogens from entering the body. They include mucus, cillia, saliva, tears, sweat, stomach acid, and the skin.
Third Line of Defense: Specific
B cells that are created in the bone marrow and reside in lymph nodes, the spleen and circulate in the blood.
Second Line of Defense Non-specific- An inflammatory response begins when a pathogen stimulates an increase in blood flow to the infected area. The capillaries dilate and pain receptors are activated to help with the infection.
Third Line of Defense: Specific
T cells with specific receptor site gets activated when combines with specific antigen.
Second Line of Defense: Non-specific- The second line of defense destroy invaders that includes phagocytes which engulf foreign pathogens in the body.
Natural Killer cells respond to cytokine messages that help with communication. They also attack cells and attack enzymes called "granzymes".
Finally, interferons is a chemical that interferes with the ability of viruses to attack other body cells.
Protective proteins attack pathogens and prevent them from reproducing.
Third Line of Defense: Specific- When the first and second lines of defense fail to help and prevent infection, the specific line of defense comes in. It takes 5-7 days for this line of defense to be activated. Once the B cells limit the threat of infection, the plasma cells can also go through apoptosis and become memory cells. They can divide and produce the correct type of antibody.
They can bind to specific antigens with the help of cytokine of T helper cells. It then goes through mitosis that creates plasma cells which creates antibodies capable of combining with and neutralizing a particular antigen
Third Line of Defense: Specific- T cells are created in the bone marrow and mature in the thymus gland that help rid viruses and cancer cells. Furthermore, they cannot recognize an antigen without help so they need macrophages to help the process. Also, cytotoxic T cells bind a virus and perforates the cell membrane to deliver enzymes that causes apoptosis.
T cells can also make clones either cytotoxic cells or helper T cells to rid antigens quickly.
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