The screwdriver is like an enzyme because it is what changes the substrate (wood.)
The wood boards are like substrates because they are what is being put together to create a product.
The hole where the screw is being put in is like the active site because this is where the substrates (wood boards) become a product
When all of the parts are connected (screwdriver, screw, and hole) they represent a enzyme-substrate complex because it contains all of the needed parts to make the product.
The desk is like the product because it is the result of the screwdriver's and wood's interaction similar to how a product is a result of an enzyme's and substrate(s)' reaction