Antibiotic Resistance Project Pt. 1

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Antibiotic Resistance Project Pt. 1
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  • Doctor, I was doing some research into the work we did last week and I found something about antibiotic resistance. What exactly is that?
  • Well if you use something too much, like an antibiotic, your body tends to build a resistance or immunity to it over time. It stops working for that person and then we have to give them something else to treat whatever infection they have. This is antibiotic overuse.
  • Well then, if that person can't take antibiotics because they have resistance, then what do we give them to fight the infection?
  • We  could give them something stronger or a kind of "super drug" if you will. But there's no real way to get rid of the resistance your body has already worked up, unfortunately. We can't un-teach your body to not resist the drug.
  • If it's such a problem and there's functionally no way to treat it, then how did we let it go unchecked for so long? How did it come to be?
  • Well, antibiotics, specifically one of the best known ones Penicillin, was discovered in 1928 by accident.  
  • A biologist named Alexander Fleming left a Petri dish  uncovered overnight and the next day discovered the fungi that penicillin is from had grown in the Petri dish.
  • So antibiotics have been around for about 90 years now, and people still have immunity to them. Meaning that we must use or have used antibiotics for more things than just human medical treatment. Right?
  • Correct. As well as using it to treat human infections, we also were using it agriculturally in 1948. This happened a bit by accident as well.
  • An animal nutritionist, Robert Stokstad and a biochemist, Thomas Jukes were working with a company to enhance the growth of chickens and raise poultry profits. They started by experimenting with the vitamin B12, which boosted animal growth. But then they found that Streptomyces aureofaciens, The bacteria tetracyclines are are derived from holds more of that vitamin. The company Stokstad and Jukes were working for produced Streptomyces aureofaciens so they had access to a lot of it and it was cheaper than what they could have used, being liver extract. The chickens given the supplement grew 24 precent more than the others starting a chain of antibiotic injections for animals.
  • Original Size
  • Antibiotic bacteria added - 24% bigger
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