Dennis and Mac are friends that were working on the same ranch. There was a plague and Dennis and Mac went to find survivors. Dennis and Mac had been on the road for a while just driving.
Dennis and Mac arrived at a city and stopped. They saw a huge group of plague victims running toward them. They realize the plague victims have turned into zombies.
Dennis and Mac arrive at a gas station while they where gathering supplies a zombie comes out of the bathroom. Mac yells for Dennis and Dennis throws cans at the zombie. Then a boy named Jeremiah comes out of the other bathroom. Dennis tells Mac how a girl named Anna was calling for help over the radio. They drive to Anna's city to find her. A zombie scratches Anna's leg and she starts to turn into a zombie.
They decide to go to the radio station to see if the DJ is still alive. They arrive at the radio station and on their way inside a hoard of zombies surrounds them. Anna starts to choke Mac and she won't let go.
Petey the DJ comes out of the radio station with a radio playing blue grass music. The zombies from around turn around and run away. The key to turning zombies back to humans is by playing music and talking to them.
Mac, Dennis, Jeremiah, and Anna decide to go into the radio station and join with Petey to save the people and stop the zombies.