the Jews vs the Nazis is the main conflict because if it wasn't for the Nazis being so discriminant of their religion they wouldn't have had to hide in the annex and worry about everything they do. so they would've had normal lives if this conflict wouldn't have happened.
The Burglars vs The group was a big conflict because when the burglars came this made them worry about getting caught and made them more cautious about certain things. it also costed them a lot of things that were essential to living.
The war weapons affect the group because at night the sounds of the weapons keep the group in the Annex up and makes them very tired from lack of sleep. it also affects them because it may worry them about if they might get caught since they are right outside the annex.