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Immune system #3
The first line of defense against TB are epithelial cells in the airway, and phagocytes such as neutrophils, monocytes and dendritic cells.
Macrophages and T cells are the Primary fighters against TB, but not the first.
How they work
Epithelial cells in the airway act as a physical barrier recognizing the pathogen, then changing the surface of the airway, Trying to stop pathogenic growth.
Neutrophils are mostly present in big numbers in the defense line. They sense the bacteria then ingest the bacteria and realease neutrophil peptides, eventually killing the myobacteria.
T cells recognize the bacteria and release cytotoxic proteins which target infected cells and program the death of the infected cell, killing them.
Macrophages eliminate and restict the spreading TB bacteria using an effector mechanism.