Updated: 2/19/2021

Storyboard Description

Immune system #3

Storyboard Text

  • The Defense
  • The first line of defense against TB are epithelial cells in the airway, and phagocytes such as neutrophils, monocytes and dendritic cells.
  • Macrophages and T cells are the Primary fighters against TB, but not the first.
  • How they work
  • Epithelial cells in the airway act as a physical barrier recognizing the pathogen, then changing the surface of the airway, Trying to stop pathogenic growth.
  • Neutrophils are mostly present in big numbers in the defense line. They sense the bacteria then ingest the bacteria and realease neutrophil peptides, eventually killing the myobacteria.
  • Continuation
  • T cells recognize the bacteria and release cytotoxic proteins which target infected cells and program the death of the infected cell, killing them.
  • Macrophages eliminate and restict the spreading TB bacteria using an effector mechanism.