The colonists wanted to settle in the new world so they traveled all the way to Roanoke. The land was perfect but there was one problem. The native american's were already living there so they were nice to them.
Everything was going great in Roanoke. Everyone was happy and John Whites daughter had a baby. That meant that John White had to go back to England to get more supplies.
I choose scenario 3 because it is very reasonable that the colonists went back to get food because there is no water and you will run out of food after waiting for a very long time. The colonists were never found is because there was severe tidewater near Roanoke. Also, the region was in drought.