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  • I'm so tired. I have used so much ATP while lifting weights today.  I bet you are wondering where I get all this ATP. Well let me tell you, it starts in your cells cytoplasm in the process called, glycolysis. 
  • Glycolysis begins when you consume glucose, you get glucose from yummy food like here at this restaurant. Glucose will be split, by the two ATP molecules we needed to invest, into 2 G3P molecules but then 2 NAD+ accepts the hydrogen ions to make 2 pyruvates from the G3P and 2 NADH
  • No we are going to travel to the mitochondrial matrix, the site of the Krebs cycle. The process starts with the 2 pyruvates we got from glycolysis. The 2 pyruvates give off one CO2 molecule each and give off one H+ to make 2 NADH and to turn the pyruvates into a 2 carbon Acetyl-CoA.  Turning the 2 pyruvates to 2 acetyl-CoA in called pyruvic oxidations
  • Next in the Krebs cycle, the acetyl-CoA bonds to a 4 carbon molecule with the help of the enzyme CoA, this results in citric acid. Then the citric acid keeps going, giving up its H+ ions to NAD+ to make NADH and FADH2. After this, we will result in a total of 8 NADH and 2 FADH2.
  • Next, we move to the inner membrane of the mitochondria. Here the electron transport chain will take over to make us a lot of ATP. The high energy molecule, NADH, and FADH2 will power protons pumps to move hydrogen ions from the matrix to the intermembrane space, creating a gradient. 
  • C6H12O6 + 6O2 → 6CO2 + 6H2O + 38 ATP
  • Now that the gradient has been made, the hydrogen ions will move through the channel containing the enzyme, ATP synthase, making 34 ATP. With the 2 ATP from glycolysis and the 2 from the Krebs cycle, one molecule of glucose has successfully made 38 ATP. This my friends are how I get the energy to lift weights.
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