Updated: 2/20/2021

Storyboard Text

  • Did you know sickle cell anemia is an inherited group of disorders, red blood cells contort into a sickle shape.
  • That's interesting. I know that some treatmnets include medications, blood transfusions, and rarely a bone-marrow transplant.
  • Sickle cell anemia is is inherited as an autosomal recessive trait. Patients who inherit hemoglobin S in a homozygous autosomal recessive fashion (Hb SS) have sickle cell anemia, while those who are heterozygous have sickle trait (Hb AS).
  • This is a normal red blood cell
  • People who carry the sickle cell, carry one of the genes that cause sickle cell disease, but do not have the condition.
  • Wow! Did you know that If two copies of the Hb S gene mutation are detected, then the person has sickle cell disease.
  • Sickle cell anemia is a genetic condition that has an autosomal recessive inheritance pattern. The condition isn't linked to the sex chromosomes. Someone must receive two copies of a recessive allele in order to have the condition.
  • Sickle cell disease is a hereditary disease seen most often among people of African ancestry. The inheritance pattern is autosomal recessive.
  • This is a sickle cell
  • Sickle cell anemia is not an X-linked disease. However data shows that males are predominance of sickle cell
  • Sickle cell trait is an inherited blood disorder that affects 1 million to 3 million Americans and 8 to 10 percent of African Americans. Also affects Hispanics, Asians, Caucasians, and Middle Eastern countries.
  • The national median life expectancy is 42–47 years. People with sickle cell face many challenges, including severe pain episodes, stroke, and organ damage.