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In the year 1346, it was the middle ages and the plague had just spread to Europe.
The disease was originally on rodents witch spread to the insects around them and then the humans
The insects and fleas infected the humans by biting them
Symptoms involved large black and red boils. It is very painful and most died within 72 hours. There was no cure and no way for them to relieve their pain.
The plague was responsible for approximately 20 million deaths, 1 third of medieval Europe's population.
The main reason the plague spread so quickly was, because of the uncleanliness of the people. They did not wash their hands and rarely was their bodies.