Off the river in California, two migrant workers, George and Lennie. Travel to a ranch for new work, because during the last job Lennie mistakenly grabbed a women by her dress.
George is always on top of Lennie when he is in the wrong, Lennie's constantly battling his mental disability that makes him act different from everyone else, Lennie suffers remembering even the smallest things.
Curly, the boss son, immediately dislikes lennie because of petty issues so he makes fun of him, the wife stirs up problems by always seeking attention
Lennie was given a rabbit by slim, so he's in the barn tending it, then curley's wife walks in and they begin talking and without realizing it lennie starts grabbing her hair because he like soft things when he's nervouse then she tells him to stop and he panics and breaks her neck
lennie now caught up, he was given special instructions by george that if anything happened he should hide near a river and wait
"Hide by the river and wait for george"
george talks to himself into putting down lennie for the sake of others, and he shoots lennie before curley can get to him, letting lennie die a happy way looking the other way dreaming..