The colonists merged with the Croatoan tribe, probably because they were starving due to a drought.
The colonists were all killed by the Croatoans
The colonists set sail for England and were shipwrecked.
The colonists merged with the Croatoan tribe probably because they were starving due to a drought. I believe this because the Croatians name was carved into the tree where the colonists were supposed to be if they had to move and the Croatians had lighter eyes and skin.
The Croatoan Tribe killed the colonists and wrote Croatoan on the tree to take credit for killing the colonists. The colonists' bodies were most likely eaten by animals or washed away.
After about a year or so, the colonists think something has happened to White and he will not be returning so in the last effort, they build their own ship to try to return to England but were killed when their ship did not hold up well against a storm.