"Come, you spirits that tend on mortal thoughts, unsex me here, and fill me from the crown to the toe top-full of direst cruelty. Make thick my blood" (1.5.47-50).This quote represents both a gender and a supernatural motif. Lady Macbeth speaks out to the supernatural and asks that they unsex her and not associate her with any feminine traits. Macbeth challenges gender roles by saying this.
"As we shall make our griefs and clamor roar upon his death?" (1.7.90-91)."False face must hide what the false heart doth know" (1.7.95-96).Macbeth and Lady Macbeth both agree upon the plan to kill Duncan.