Precious is abused by her father and mother. Her father raped her and got her pregnant twice with her kids Little Mongo and Abdul. Little Mongo doesn't stay with her though because of her condition and Precious is too young to take of her. She soon got kicked out of middle school so she has no education.
Precious starts attending Each One Teach One and gaining knowledge. Although, she gets kicked by her mother because her mother stopped getting welfare from Little Mongo's condition. Since she got kicked out she has to start making decisions for herself and Abdul. In the process of all this she finds out that she has AIDS and is worried it Abdul has them too.
Precious finds a halfway house to live in. She is also happy that her son, Abdul, doesn't have AIDS. She eventually gains her education and accepts that she has a sickness( HIV ). She overcomes abuse, poverty, teenage motherhood, rape, illiteracy, and all the odds that were against her.