Hello Guys, welcome to 79 News on the Go. Today, I am joined with Dr. Shah to talk about the E-Coli infection.
So lets begin, can you please start by just telling us a bit about E-Coli.
E-Coli is a type of bacteria that normally lives in the intestines of humans and in some cases is found in the gut of some animals as well.
Most E-Coli are harmless and keep you digestive tract healthy however some cause unpleasant symptoms.
Oh, very interesting. Now can you please inform us on some symptoms of E-Coli
Symptoms of E-Coli typically begin around three to four days after having exposure to the bacteria. However, you could become ill as soon as one day or after a week.
These are nausea, vomiting, abdominal pain, diarrhea that is often bloody, high fever, malaise, a loss of appetite and mild dehydration.
The E-Coli infection has numerous symptoms that start to appear when one has caught the infection.
E-Coli easily penetrates the body’s first line of defense as it is hidden in our food so it just travels along to our stomach. It is powerful enough that it can survive with your strong stomach acid.
When the body detects micro-organisms that are not native, phagocytes that are in the bloodstream engulf and destroy the bacterial cells.
If this is still not enough, then lymphocyte cells generate a response in which the bacteria is identified as a foreign mico-organism. These attach onto the E-Coli’s specific antigens and this is done using antibodies.
After that, the E-Coli attaches itself to the intestines and releases toxins which causes many of the symptoms that are felt.
Wow, that is absolutely fascinating. Please tell us more on antigens and what happens when E-Coli infects a host
The bacterium latches onto the host cell using long protein filaments called pili. Then bacterium use a syringe type mechanism to inject bacterial proteins into the cell.
Although most E-Coli bacteria is harmless, certain pathogenic strains can infect the human intestinal tract, causing the symptoms and very rarely death.
Now more about E-Coli infecting the host
As antigens are specific to their pathogen, it does not take as long to produce more antibodies in case it is detected again in the body.
Please Sir, continue with your explanations on how it infects the host and more about how it spreads
E-Coli is spread through fecal contamination of food and/or water, especially in raw or undercooked meat, unpasteurised milk and raw fruits and vegetables.
Some of these proteins become receptors in the host cell’s membrane, which help the bacteria bind firmly to the cell’s surface. As more and more bacteria bind to the intestinal lining, diarrhea and other symptoms of the infection begin to appear.