Cov-SARS-2 at first is stopped by the nonspecific barriers, the skin. It then finds an opening, the mouth, to enter the body through.
I'm COV-SARS-2! Oh no, not a nonspecific barrier, I must find a way around. Oh look, there's an opening.
I'm a gatekeeper (Mast Cell). Oh no, there's a zombie (pathogen), I need to call (secrete histamines) the dogs (macrophages).
The dog (macrophage), after being alerted by the call (histamines) from the gatekeeper (Mast Cell), attacks the zombie (pathogen) before going to the messenger (helper T Cell).
I'm a Macrophage!*chomp*
The macrophage (dog) goes to the Helper T (messenger), showing the antigen (zombie bit) to activate the adaptive immunity (defense).
I am a messenger (helper T Cell)
I need to bring the zombie foot (antigen) to the messenger (helper T Cell)
*Due to a beekeeper's inability to divide, and only having six boxes, I skipped the part where the B cell divides into plasma cells and memory cells. In real life, a B cell would divide when activated. Apologies for the lack of accuracy here.
Guys, zombies are here!!!! (activating the adaptive immune system at the lymph node)
I'm a knight (killer T Cell)
I'm a soldier (regulatory T Cell)
I'm a beekeeper (B cell)*
The knight (Killer T Cell) attacks (secrets chemicals) the infected townsperson (infected cell), killing it (forcing it to destroy itself).
Now I can more easily kill the zombie (pathogen), since the bees attacked (neutralized the pathogen)!
Bees, attack! (antibody secretion)
I'm an infected cell. No one will notice me.. Oh no! Not a knight (killer T cell)!
**Sorry if this part is too gory for school, and the infected cell could not be lying down due to position constraints. ***I didn't show what would happen if the immune system was not deactivated due to the limitation of only having six boxes.
Guys, we did it! The zombie is dead! Now stop, you can go home. (deactivating adaptive immune response)***