As a small child, it was very clear that Matilda was a very gifted girl, however no one ever paid attention to her and thus her abilities went unnoticed.
In 2009 a genetically re-engineered measles virus originally used to cure cancer turns into a lethal strain that wipes out most of Earth's population and turns those infected into vampire mutants.
In Charles Dickens's "Christmas Carol" Scrooge is an ill-tempered old man who's rude and mean to everyone. He gets visited by the "Ghost of Christmas Yet To Come" who shows Scrooge his future.
As Matilda grew older she became more and more familiar with her gifts and as a result she was able to use them against Miss Trunchbull and rid the school of her barbaric rule.
Three years later New York is in complete ruins and void of humans. Dr. Robert Neville is surviving alone in the ruins of New York trying to find a cure and unsure if there are any other uninfected humans left alive.
Scrooge's future sees him dying and people taking comfort and happiness in his death. Scrooge asks the ghost to give him a chance to change himself. Scrooge wakes up and sees that it is Christmas morning. He changes himself for the better and becomes kind and generous.