It has been about two months since the disappearance of Hyde. Jekyll tarts to socialise more with friends and Utterson.
Hyde suddenly shuts out Utterson for no apparent reason.
Utterson decides to pay Lanyon, and sees that Lanyon is not well. Utterson asks if he has seen Jekyll, which makes Lanyon return by saying he doesn't want to hear of Jekyll, and regards him as "dead".
When he gets home, Utterson writes to Jekyll asking him why he has barred him from his life, and why Lanyon would say such a thing.
Utterson receives a reply the next day, saying that he doesn't blame Lanyon for the end of their friendship and agrees it must be over. He also asks Utterson not to be surprised if he refuses to see him.