Come, you spirits That tend on mortal thoughts, unsex me here, And fill me from the crown to the toe top-full Of direst cruelty. Make thick my blood.
Act II, Scene II
During Scene III of Act I, the witches meet with Macbeth and Banquo and prophesy their future. Macbeth's prophesy is to become the Thane of Cawdor and "King hereafter", meanwhile Banquo is foreseen to have a linage of kings.
Act II, Scene III
In Scene V of Act I, Lady Macbeth reads a note from Macbeth about what the witches did to him. After that, she asks the witches to overcome her and take the femininity out of her so she can become ruthless and cold-hearted.
Act III, Scene II
Scene II of Act II is the climax of the story where Macbeth, our main protagonist, has given in to the witches prophesy about him and killed Duncan. Little does he know, this is only the beginning to the possession he will be under.
Act III, Scene III
Macduff and Lennox show up to check on the King and found that he's been murdered. Macbeth claims that he killed the guards out of his love for the King. Meanwhile, Malcolm and Donaldbain, Duncan's sons, flee the castle in hopes to seek refuge.
During this scene, Macbeth and Lady Macbeth have some sort of mind-refresher conversation in order to get prepared for their plans that night. Although their minds are full of the overwhelming possession of the evil they've done, they must still continue life and act innocent.
After Macbeth talked to the murderers in Scene I of Act III, they went after Banquo and his son, Fleance, in a mission to kill them. They successfully kill Banquo, meanwhile Fleance gets away.