In order to keep your own body from destroying your new liver, you must take immunosuppressant drugs
Is this why it gets inflamed after surgery?
Your Macrophages will identify the new liver as a foreign object and natural killer cells will immediately take action.
Yes. The drugs we are prescribing act similar to Suppressor T Cells and interleukin in regulating the production of harmful agents and Helper T Cells to protect your new liver.
But I don’t want to take pills for the rest of my life!
Without the drugs to stop your humoral response, B Cells will release the antibodies that will destroy you new liver and then the remaining “threats” (parts of your liver) would be digested by the enzymes in nearby lysosomes.
That sounds painful!
Although the liver isn’t a virus or bacteria, it is still viewed as an antigen, so the Cytotoxic T cells in your body will attack it because your cell mediated response is for leukocytes to be released.
Then can’t you just give me a vaccine instead?
It is your own body and not a disease, we can’t just give you a vaccine because it is a natural response. You have take the drugs everyday to protect yourself.