History of DNA Assignment
Updated: 12/17/2020
History of DNA Assignment

Storyboard Text

  • The British Ministry of Health, London 1928
  • A microbiologist named Frederick Griffith studied Streptococcus pneumoniae, a bacteria that causes the the deadly lung disease, Pneumonia.
  • Griffith compared two forms of the disease, the S-strain which was highly pathogenic but could be made non-pathogenic by heating it, and the R-strain which was non-pathogenic.
  • He created an experiment in which he injected different strands, and mixtures of strands of the bacteria into mice and observed what happened to them.
  • Griffith noticed that the mice died after being injected with the living S-strain bacteria, as well as a mixture of heat-killed S-strain bacteria and living R-strain bacteria, while the mice lived when the R-strain bacteria and just the heat-killed S-strain bacteria were injected.
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  • He concluded that the S-strain had somehow passed on its deadly properties to the live, non-pathogenic R-strain. He called this phenomenon, "The Transforming Principle".
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