The cursed Thebes royal family's daughter Antigone, & sister Ismene, are entrusted to uncle/King Creon. Her brothers, Polyneices & Eteocles, both died when Polyneices tried to usurp the throne.
Creon decrees that Eteocles will be buried with honor, but Polyneices will be disgraced, his body left for the birds and dogs. Going against the king means death! Nevertheless, Antigone is determined to bury her brother, Polyneices.
Guards report to Creon that Polyneices' body has been found buried, with proper ceremony. The Chorus says that it is of the gods. Antigone is then brought to Creon, having been caught in the act of re-bury her brother. Her fate seems doomed.
Creon and Antigone argue back and forth whether it is right to obey the law or obey the gods. Isomeme is found also guilty as a co-conspirator. Thebes sides with Antigone, and Haemon argues for Antigone; Creon does not listen to him nor Teiresias, the prophet, whose word always comes true.
Antigone is taken away to be left in her tomb. Creon decides to reverse the curse. After burying Polyneices, he goes to free Antigone, but Haemon is sobbing over her, as she has hanged herself.
Tragedy prevails. Haemon strikes out at Creon, but then turns the sword on himself. Eurydice, also kills herself. Creon is left alone & miserable. He wants a death of suffering, & to live out the rest of his life with shame & regret. The Chorus warns that wisdom is the key to a good life.