SIRNA Storybard

SIRNA Storybard
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  • Everybody knows what AIDS and HIV is, but not many people know the treatments behind it and what scientists are doing to try and improve these treatments.
  • That's why we're here today! Turns out, the method that is currently being used is good, but not good enough, so scientists are trying to develop a new approach with something called RNAi.
  • RNA is part of your genetic material, and RNAi is a technique that stops certain things in your DNA from being expressed, by using "small interference RNA" (siRNA).
  • Using RNAi has made improvements in the fight against HIV by targeting the same cells that HIV-1 target, lymphoid and myeloid cells. siRNA targets certain mRNA's of HIV and blocks it, and might prevent it from expressing​ and replicating.
  • True, but that might not work because those cells are important to your immune system!
  • That is only one option, though! They could also target it in the cytoplasm or in other types of cells.
  • Currently, there isn't a way to efficiently deliver siRNA molecules to HIV infected target cells.
  • What needs to be done to improve current and future clinical status of RNA therapeutics?
  • Years of research and clinical trials will be required to improve RNA therapeutic treatments to be effectively used on HIV cure
  • Cannot wait for scientists to discover a way to cure HIV!
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