Discovery of DNA - 2
Updated: 3/9/2021
Discovery of DNA - 2

Storyboard Text

  • Research Lab
  • Protein
  • DNA
  • RNA
  • By 1944, researchers by the names of Oswald Avery, Colin MacLeod, and Maclyn McCarty wanted to continue the work of Griffith and started by growing bacteria in liquid cultures
  • The researchers had to prepare 3 identical extracts of the heat killed S-strain bacteria. This was accomplished by isolating the bacteria, disrupting the cell membranes and collecting the cell contents.
  • RNA destroying enzyme mixture
  • Protein destroying enzyme mixture
  • X
  • X
  • They added a different enzyme to each extract. One to destroy protein, one to destroy RNA, and one to destroy DNA. The goal was to find out which of the 3 was responsible for and caused the transformations.
  • Responsible for passing down genetic information
  • Each enzyme-treated extract was mixed with live R-strain cells. All three mixtures were investigated to find out which enzyme addition revealed the answer to these transformations.
  • The mixture that left the R-strain as non-pathogenic was the one containing DNA-destroying enzymes. This means the DNA is responsible for the transformation and for passing down genetic information in general.
  • DNA destroying enzyme mixture
  • The researchers were thrilled with their discovery that DNA was structure that contained and passed down genetic information. This would be a guide for scientists to further their study on DNA.