It crosses through Maine which becomes a free state. It got passed on March 12, 1820. What caused the Missouri compromise to happen was it needed to disable the sectional and political rivalries in Missouri in late 1819. The effect it had was the Americans wanted to split the countries in half making it 22.
The Wilmot Proviso
When He beat John C. Breckinridge and Stephen A. Douglas. Both candidates weren't happy because they were beaten. The cause of it was because slavery was used and they had a problem with it. The effect it had was Abrham Lincoln promised that Slavery wouldn't happen anymore.
Attack on Fort Sumter
It led a small army. Also It was a free state along with Idaho into it. The cause it had was it wanted to start an attempted slave revolt and destroy slavery. The effect John Brown's raid had was it made the Southerners get scared because of what was happening.
Uncle Tom's Cabin
When they had to take out slavery because of the Mexican war. It had a free state of Ohio and it got passed in the year 1846. What caused for it to happen was they wanted to take out slavery. And the effect it had was they negotiated the terms.
Confederate states wanted to give up and start a new war. Because the South Carolina had it's state passed on April 12, 1861. What caused for the Attack On Fort Sumter to happen was No union ships were bombed. But the effect it had was they wanted to destroy Fort Sumter and attack them and sure enough they succeeded.
It helped Fugitive Acts make it a crime. He wanted the Civil war to stop. The Cause Uncle Tom's Cabin had was the attitudes in the North were reused because he used content. But Uncle Tom's Cabin effect was it made the North be more attached to slavery.