Hey, Check us out! We're pretending to be DNA replicating! Wanna Play!
I totally want to. I'll be the enzymes Helicase that binds to pull DNA apart and Primase that binds to it after it comes apart.
We need a replication fork though to be the middle part that allows your DNA to replicate.
Look at me. I'm the lagging strand that runs 5' to 3'. We're already replicating! This is so cool! Thanks for being our enzymes!
Hahaha!! I'm standing on my head to be the leading strand, the complimentary strand running from 3'to5'. I feel a little light headed here!!
You guys are so funny! Okay so I know how to be the enzyme, polymerase, for the leading line to zip it up and bind it together. But I'm not sure how to zip up the lagging line. I can only go right to left.
Oh no! We better figure this out soon! The blood is rushing to my head!
Hey, I've been watching you guys and I have a solution for your replication problem. It's Okazaki Fragments. They will help bind the lagging line of DNA after replication.
Whew! I'm happy to be off my head! Am I replicated now?
Yes and No.
We thought it was as easy as separate and bind?
Well it is...
And it isn't...
The Nitrogen bases attach to the replicated complementary bases.
And hopefully it all goes smoothly with no mutations. Or we might be looking at an X-men thing happening soon! Just kidding!