Storyboard: To Immunity and Beyond
Updated: 9/24/2020
Storyboard: To Immunity and Beyond

Storyboard Description

Storyboard for Teach an Old Gene New Tricks

Storyboard Text

  • Pathogen Enters The Body
  • Cough
  • Measles
  • Blood Cells React
  • Where are we?
  • Time to infect
  • We broke past the last two of defence. We got this!
  • Inside the body
  • Measles Antigens
  • B-cells attack the Measles Pathogen
  • Fight to the end
  • Get them with your Antibodies
  • Me too
  • B-cells
  • I can not bind to it
  • That means we are to late.
  • The B-cells bound onto my antigen
  • Bind onto them with your antibodies
  • Whats this?
  • When a pathogen goes through the body it activates the First and Second lines of defence before it triggers the Third line of defence. The first and second lines of defences are both non-specific defence mechanism that target a variety of pathogens. Measles is a virus that enters the body through the mouth, nose or eyes. We will be following Measles as it enters the bloodstream and fights B-cells.
  • B-cells clone
  • Clones attack
  • Get it
  • The body is aware that there is a foreign pathogen, in this case Measles inside it. The body knows it is foreign because this pathogen is unrecognisable by the body, and the pathogen would have broken past the first and second lines of defence. The body then sends special type of white blood cells called B-cells(Lymphocyte) to find the pathogen. Once it has found the measles pathogen, the cells can start fighting it. During this waiting period we often feel sick as the virus is infecting the body which is how rashes, and other symptoms are caused. The reason it takes so long for the B-cells to react is because the third layer is a specific defence mechanism, which takes a while for the B-Cell to be able to match the pathogens antigen with the correct B-Cell antibody.
  • B-cells Destroy The Pathogen
  • There no escape
  • Retreat
  • It is to late we have lost
  • The B-cells then try to connect the Measles pathogen’s antigens with antibodies. Antibodies are made up of protein and their sole purpose is to bind onto and kill pathogens. Each pathogen has a unique antigens therefore it needs a unique antibody to fight it.
  • Memory Cells Store Information of Pathogen
  • That pathogen had some unique antigens
  • Tell me about it. I'm going to remember it for a ever.
  • Their not that weird im collecting them
  • When the body finds the right B-cell with the antibody that connects with the measles pathogen’s antigens. The B-cell then clones itself to cover all antigens on the measles pathogen with antibodies. By cloning itself the B-cells can fight the measles pathogen easier and more efficiently as B cells are specific defences mechanisms.
  • Don't let it infect the cells
  • Bind onto all the antigens
  • Im being surrounded
  • B-cells antibody
  • Clones of the B-cell
  • Don't stop until they are all dead
  • With the cloning of the B-cells many antibodies are also created. They then attack the measles pathogen by attaching the B-cells antibodies to the measles antigens to allow other immune cells to then efficiently destroy the measles pathogen. This brings an end to your sickness and the Measles pathogen’s invasion in your body.
  • They stand no chance
  • Destroy them
  • I've killed one
  • When the Measles Pathogen is destroyed there are many Antibodies and B-cells that remember the Measles pathogen and its antigens. The remaining antibody and B-cell information is now stored in the memory B-cells. The memory B-cells stay in the blood stream ready to fight the Measles Pathogen. If the Measles pathogen were to re-enter the body, the memory B-cells would know what to do and remember which Antibodies are needed to destroy it. Therefore, creating immunity to Measles as the body can destroyit easily and before the person gets sick.
  • Tell me about the battle and i'll take those antibodies too
  • Memory B-cells
  • Okay you better remember all the details for when it comes back.