BIOL 343 HW #6

BIOL 343 HW #6

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  • Instead of watching TV how about I tell you a story about how a phage attacked an innocent cell.
  • Ugh fine dad.
  • Chapter 1: Attachment An innocent eukaryotic cell was wandering the body just minding its own business when a mean and scary RNA virus came along and attacked the cell. The virus managed to attach and hold onto the cell even though the cell tried to resist.
  • But how did the virus attach if the cell didn't want it to?
  • Great question! The virus is able to attach to the existing receptors on the cell membrane. Finishing the chapter, it says that once the virus attached to the cell it manipulates the cell into allowing the virus DNA to enter the cell.
  • Keep going!
  • Glad you're enjoying the story! Chapter 2: Penetration This virus has a strong envelope around it so it enters the cell by fusion with the cell plasma membrane. The virus' receptors fuse into the membrane of the cell and the nucleocapsid enters the cell.
  • What if the virus didn't have an envelope?
  •  Well then the virus would have to enter the cell through endocytosis. Chapter 3: Biosynthesis Now that the virus' genetic material is in the cell, it replicates and the initially early proteins are made and then late proteins are made after. The virus can use the host cell's replication machinery.
  • Huh these viruses seem really dangerous!
  • Yes they are very good at their job. Back to the story, Chapter 4: Assembly The components that are formed in the cytoplasm of the cell are able to self assemble. The late proteins are very important in this assembly of the new phage particles.
  • Wait where did these new components get made?
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