Tamoxifen

Tamoxifen
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Storyboard Description

Good evening, Congratulations on your remission! The Dr. has written a new prescription for tamoxifen 20mg once a day to be taken for the next 5 years. This is to prevent the cancer from returning.

Storyboard Text

  • Thank you so much. What is the tamoxifen used for?
  • Congratulations on your news of remission from breast cancer. The Dr has prescribed 20mg a day of Tamoxifen to be taken for the next 5 years. I'm going to go over some information you need to know. 
  • Are there any potential complications that I should be aware of?
  • Tamoxifen is a selective estrogen receptor modulator. This means it competes with estrogen for the binding sites in the breast and surrounding tissues. This reduces DNA reproduction of the bad cells, thus suppressing tumor growth lowering the chance recurrence of breast cancer in high risk patients.
  • This means if i feel a pain in my leg when I extend it and try to flex my toes then I should seek medical attention as soon as possible? Also, is there any specific way or time I should take this medication?
  • I'm going to go over life threatening adverse reactions that you need to notify your Dr if you experience them. This includes thromboembolism this would be any signs or symptoms of a blood clot that could potentially move to your heart and lungs or even your head causing a stroke.
  • Reference: Vallerand, A.H. & Sanoski, C.A.(2017) Davis's Drug Guide for Nurses (15th ed.). Philadelphia, PA: Davis
  • I will make a note of that. Are there any other side effects that may occur?
  • Also some less severe side effects that are seen with this medication are confusion, depression, headache, weakness, blurred vision, edema, nausea, vomiting, vaginal bleeding, hot flashes, and bone pain. Make sure you follow up and receive blood work as it is ordered so that blood levels may be monitored
  • Reference: Vallerand, A.H. & Sanoski, C.A.(2017) Davis's Drug Guide for Nurses (15th ed.). Philadelphia, PA: Davis
  • Ok. Are there any drug interactions I should know about?
  • That is correct. As far as taking your medication you need to take it as directed, if a dose is missed then skip it and resume taking the medication at the next dose time. If you have any bone pain then report this as soon as possible this could mean the medication is working however pain medication can be given to help with comfort.
  • Reference: Vallerand, A.H. & Sanoski, C.A.(2017) Davis's Drug Guide for Nurses (15th ed.). Philadelphia, PA: Davis
  • Very good question. If you are taking warfarin then tamoxifen can increase the effectiveness causing you to bleed more easily. If you are taking estrogen then tamoxifen effectiveness is reduced.  If you have any other questions please call the office.
  • Thank you so much for the information I will call if I have any concerns.
  • Reference: Vallerand, A.H. & Sanoski, C.A.(2017) Davis's Drug Guide for Nurses (15th ed.). Philadelphia, PA: Davis
  • Reference: Vallerand, A.H. & Sanoski, C.A.(2017) Davis's Drug Guide for Nurses (15th ed.). Philadelphia, PA: Davis
  • Reference: Vallerand, A.H. & Sanoski, C.A.(2017) Davis's Drug Guide for Nurses (15th ed.). Philadelphia, PA: Davis
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