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Neurochemical explanation of nicotine addiction
Updated: 9/22/2020
Neurochemical explanation of nicotine addiction
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Storyboard Description

For Psychology AQA - Addiction Topic

Storyboard Text

  • Dopamine is a neurotransmitter which causes short term euphoria!
  • When someone takes nicotine it is released into the Mesolimbic pathway which causes pleasure and reduced stress
  • When someone takes nicotine it is released into the Mesolimbic pathway which causes pleasure and reduced stress.
  • Acetylcholine (ACh) is a neurotransmitter. the increase of this causes a decrease in dopamine
  • The ACh binds to ACh receptors (decreases dopamine). One variation (nAChR) is triggered by both ACh and nicotine
  • The Nicotine binds to the nAChR receptor causing the receptor to SHUT DOWN. This is called DOWN-REGULATION
  • Nicotine
  • nAChR
  • The nAChR receptor is no longer inhibiting the release of dopamine so dopamine release increases (sending a signal along the mesolithic pathway to the NAcc. This releases dopamine along the mesocorticol pathway to the PFC.
  • Nicotine
  • nAChR
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