The protagonist, Charlie Gordon, is a 37 year old man that has a low IQ. He wants to have an operation that makes him smart, so he hopes that the Doctors will use him. If he gets chosen, he will have the operation that can make him 3 times smarter than he already is. The operation worked on Algernon the mouse, so he hopes it works for him.
Algernon became aggressive and bit Charlie. Algernon is becoming less intelligent and is not eating or doing the maze anymore. a This is bad news for Charlie because what ever happens to Algernon will happen to him. This means Charlie will also lose his intelligence and not be able to do as much as he used too, such as reading and writing.
Charlie writes a letter to Ms. Kinnian telling her that he is leaving New York for good in hopes to find a new place where no one knows that he used to be a genius and no one feels bad for him. He then told Miss Kinnian to put flowers on Algernon's grave every week, to show that the grave does not only symbolize Algernon, it also symbolizes Charlie's intelligence.