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Muscle contraction
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الانزلاق: 1
Hey Sam, I'm having some trouble with understanding muscle contraction.
....Really? Alright Chad. I will explain to the best of my abilities.
الانزلاق: 2
So the brain's the boss?
Alright, Chad. Muscles don’t work on their own. They need instructions from the nervous system.
Exactly! The brain sends a signal to the muscle through a neuron, and that signal is called an action potential
الانزلاق: 3
The action potential travels down to the neuromuscular junction(NMJ) – where the neuron meets the muscle.
The NMJ consists of the synapse, the connection between the neuron and muscle cell.
And that's what makes the muscle contract?
Not quite yet. This is just the start!
الانزلاق: 4
When the action potential reaches the end of the neuron, voltage-gated calcium channels open, letting calcium enter
Voltage what?...
voltage gated channel, its a channel that only opens when the electric charge reaches a certain level from the action potential.
الانزلاق: 5
so calcium gets things moving?
Exactly!
it triggers the release of a neurotransmitter, a chemical by which signals are moved across the synapse.
In this case, that neurotransmitter is the acetylcholine(ACh)
الانزلاق: 6
ACh moves through the synapse and binds, to receptors on the muscle cell
When ACh binds, chemically gated channels open and allow sodium in and potassium out.
And that exchange of sodium and potassium creates an action potential in the muscle, right?
Yes and that's what makes the muscle finally contract.
الانزلاق: 7
So? Do you understand?
Hmm... I already forgot.
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