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  • Presentation
  • Hi I'm a high school biology teacher
  • Let's go to the laboratory so I can explain it better
  • And I think you really want to know how the 3 lines of defense work
  • First Line of Defense
  • The first line of defense includes physical and chemical barriers that are always ready and prepared to defend the body from infection.Examples: Tears, stomach acids, skin, mucous membranes and cilia, sweat, nonspecific, saliva, interferon,
  • As you can see, on the board I wrote down the definition and some examples of the first line of defense
  • Second Line of Defense
  • The second line of defense is nonspecific resistance that destroys invaders in a generalized way without targeting specific individuals.Examples: antibodies, specific, B cells, T cells,
  • ... and here are some examples...
  • Young 28 year old teacher, from California.That has won a price for the best teacher of the year
  • Third Line of Defense pt1
  • The third line of defense is specific, targeted resistance, which is acquired immunity. This immunity is not present at birth but is learned and tailors its attack on specific antigens because it remembers them.Examples: Fever, leukocytes, protective proteins, phagocyte, specific, Inflammatory response, Natural Killer Cells
  • ...OK, now that I finished explaining how the three lines of defense work, I'll explain and focus a little bit more on the third line of defense
  • The first line of defense is your innate immune system. Level one of this system consists of physical barriers like your skin and the mucosal lining in your respiratory tract.
  • Third Line of Defense pt2
  • The third line of defense is specific, targeted resistance, which is acquired immunity. This immunity is not present at birth but is learned and tailors its attack on specific antigens because it remembers them.Examples: Fever, leukocytes, protective proteins, phagocyte, specific, Inflammatory response, Natural Killer Cells
  • 1. Macrophage identifies and binds the invader
  • The second line of defence is a group of cells, tissues and organs that work together to protect the body. This is the immune system.
  • Third Line of Defense pt3
  • The third line of defense is specific, targeted resistance, which is acquired immunity. This immunity is not present at birth but is learned and tailors its attack on specific antigens because it remembers them.Examples: Fever, leukocytes, protective proteins, phagocyte, specific, Inflammatory response, Natural Killer Cells
  • Lysosome
  • The third line of defense is specific resistance. This system relies on antigens, which are specific substances found in foreign microbes.
  • Look at the little board
  • Third line of defense image explanation step by step pt1The Macrophage identifies the invader and decides to bind it so it can eliminate, afterwards the invader gets engulfed so the process of the invader extermination can begin.
  • 2. The invader gets engulfed
  • Third line of defense image explanation pt2When the invader is destroyed with the help of the lysosomes the Macrophage will sound the alarm and is going to produce Cytokines
  • 3. The invader is destroyed with the help of the lysosomes
  • 4. Macrophage sounds the alarm
  • Virus destroyed
  • Cytokines
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