inflammation and healing
Texto del Guión Gráfico
- My friend George is going to demonstrate the process of inflammation and healing.As you can see he has fallen and scraped his knee, which has now caused cellular injury, the beginning of the inflammation process.Mast cell degranulation has caused the release of histamine! Chemotactic factors have also alerted the white blood cells about where the site of injury is.
- I've fallen and now I'm bleeding! I hope this stops soon!
- Now he's found a place to sit. By this time the vascular response has begun. The histamine that was released causes vasodilation and increased capillary permeability, he may also see a form of exudate!
- My knee hurts so much! It's red, warm, swollen and theres all of this bloody stuff coming out of it!
- Now the cellular response has begun. Now that the White Blood Cells have found the site of injury they begin pavementing, where they stick to the vessels in the area. Leukocytes are also joining the party by a process of emigration.Our friends neutrophils and monocytes also join in to help clean the site of injury. Clotting is also taking place to stop the bleeding and begins the framework for healing.
- My doctor said something about Rice?! IM ALLERGIC!
- George is finally home! However there is one last stage. It is now the immune responses turn! A special kind of white blood cell, B cell or lymphocyte reports for duty. These B cells differentiate into plasma cells and produce antibodies for immunoglobulins.
- Are these immunogoblins scary?
- There are different kinds of immunoglobulins that are called to the scene! One of them is the IgG, is the most common one and it is responsible for memory during a secondary immune responseThere are also cells called T cells which there are a variety of. One specific cell called a T helper cell is the messenger between immune and inflammatory responses. T helper cells activate T cytotoxic cells that go directly to the antigens and kill them.
- No I don't, what do you call it?
- It has now been two weeks since we've seen George. He is all healed with a scar to prove it!Do you have anything to add about the inflammatory process George?
- What do you call it when a yellow jacket has inflammation of the liver?
- Hepatitis Bee!!
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