Unknown Story
Updated: 6/9/2020
Unknown Story

Storyboard Text

  • Scenario Two
  • Taha! Be careful with those scissors.
  • It's basophil cells that really trigger the inflammatory response!
  • Real Life...
  • Microscope Vision!
  • How the second line of defence (part of the innate immune system) protects the body from sciessor flinging people, and other pathogens.
  • Looks like Taha is about to impale me with germ-filled scissors. Luckily, my second line of defence protects me with non-specific cellular and molecular responses of the innate immune system,
  • Pathogens enter through the wound. Chemical messengers send in leukocytes and histamine, which cause blood vessels to dilate, bringing in white blood cells, and ultimately allow for tissue repair. It also causes fluid to leak out of the blood vessels, which contain protein, to wall of the area (causing inflammation). Inflammation may partner with rising temperatures, and even a fever, to combat pathogen growth.
  • Macrophages can move into body tissue in response to infection, to determine the pathogen as a foreign body. After determination from macrophages, phagocytic leukocytes engulf foreign bodies, by trapping them in a vesicle ( i.e. phagosome). Lysosomes at that point can digest the phagosome. Eosinophils also help this process by fighting parasites and aiding phagocytosis.
  • Representation of inflammation.
  • The wound will eventually clot, which is to prevent blood loss from the broken vessels, and further pathogen entry.. Damaged cells essentially signal clotting factors, where the enzyme thrombin develops fibrin, which traps blood at the damage site. Clotting factors also cause platelets to become sticky which aids in plugging the wound.
  • Hey! It'c clotting!
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