3rd Line of Defence
Storyboard Text
- Slide: 1
- I am a macrophage. I am eating this pathogen.
- Oh no! I am being eaten!
- Macrophage encounters, eats a pathogen floating in the blood.
- Slide: 2
- I am a helper T cell. I interact with the antigen and activate memory T and killer T cells specific to this pathogen.
- I will display the pathogen's antigens to helper T cells, who will activate other types of white blood cells.
- I am an antigen.
- The macrophage displays an antigen (a molecule on the outside of pathogens that signals the body to generate immune response) specific to the pathogen it ate to helper T cells. The helper T cell activates the other parts of the acquired immune system.
- Slide: 3
- I am a T cell. I interact with the helper T cell to be activated and differentiated into two types of cells.
- I connect with T cells, activating and differentiating them into Killer T cells and Memory T cells.
- I am a killer T cell. I attack and destroy cells infected with a specific pathogen.
- I am a memory T cell I remember a specific pathogen.
- T cells interact with Helper T cells, which activates and differentiates the T cells into Killer T cells and Memory T cells.
- Slide: 4
- I watch this happening from the side.
- I am shooting perforin at the infected cell.
- Killer T cells attack infected cells with perforin, a protein that binds to their cell membranes.
- Slide: 5
- I watch this happening from the side.
- I made the infected cell burst, which destroyed it.
- This causes the cell membrane to burst, and destroys the infected cell before it has a chance to help the pathogen reproduce.
- Slide: 6
- We saw the Killer T cells destroy the infected cells, which stopped the pathogen from further reproducing.
- We will make sure our body remembers these pathogens. If they come back, we will be prepared and they will be destroyed even faster.
- Memory T cells remember the pathogen, which results in a faster Killer T cell response in future infections, which would result in infected cells being more quickly destroyed, leading to less chances for the pathogen to reproduce.
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