So because there are 46 chromosomes, your cells will need to copy those chromosomes before they can move onto mitosis.
MITOSIS THAT WAY
!WANTED!CHROMOSOME WENT MISSINGREWARD - 444K
I'm Jade!
SISTER CHROMATIDS
And I'm Jude
Chromosomes have sister chromatids. Remember when we said chromosomes are shaped like an “X?” An “X” has two lines and think of those two lines as the sister chromatids.
X
MEET JADE AND JUDE: THE CHROMOSOMES
CENTROMERE
And there is a structure in the middle of the chromosomes called a centromere. Centromere is in the middle because “centro- = center,” easy to remember, right? And this centromeres hold the sister chromatids together.
Thanks to our centromere, we're stuck together now!
If we say all DNA needs to be copied before mitosis, it means that the chromosomes need to be copied.
Chromosomes have two sister chromatids.
42 Chromatids 42 Chromosomes
96 Chromatids 42 Chromosomes
Remember that the number of chromosomes IS the number of centromere. Look at the next square!
MITOSIS
ANAPHASE
METAPHASE
PROPHASE
1 Chromatid1 Chromosome (Haploid)
So when the DNA IS copied, your homologous chromosomes will now have 2 chromatids, called a diploid chromosome, but because they still only have 1 centromere, you will have just 46 chromosomes with 92 chromatids.
Before your DNA is copied, there will be only one chromatid, called a haploid chromosome, and if there is a centromere attached to it, you will still call that a chromosome because you are counting the number of centromeres it has. A normal human being has 46 chromosomes. No more. No less.
2 Chromatids 1 Chromosome (Diploid)
This is how it looks like before and after your DNA is replicated. Make sense now?
Before
After
We will remember Prophase as the first step for “pro-” meaning the beginning of mitosis.
TELOPHASE
Let's now start with the first step of mitosis! A phase called Prophase.
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