Time to go inside and find my way through this peculiar house....
Cervix
No,this door.
What way should I go?
One of these I assume.
This door.
We have no clue where either.
Agreed! Follow that sperm!
Uterus
Do not listen to them! Going to them is like shaking death´s hand.
Come here little sperm.
Ahhhhh!
I am hungry!!
Those stairs are meant to trick you. Don´t go up there. Come here let us take care of you.
Approximately 250 million sperm enter vagina, most of them die (99%) within 30 minutes.Defenses: Sperm destroyed by deadly acids that protect vagina from pathogens.
Fallopian Tubes
I do not want to die.
I have been walking for 30 minutes!
60, 000 remaining sperm must navigate through the cervix located at the far end of the vagina.Cervix usually plugged shut with mucus to defend against invading pathogens. However, duringovulation, estrogen flows from the ovary to the uterus, which softens the mucus to make itwatery so sperm can navigate through.Sperm must swim single file through tiny channels in the cervical canal. Most of them will diebecause they get stuck or lost in one of the tens of thousands of passageways.
Fertilization
Same! Let us find it. Good luck! May the fastest win.
I sense the egg!
Approximately 3000 sperm remain and must navigate through the uterus to the fallopian tube.Muscular contractions. of. the uterus will help to propel sperm in the direction of the correctfallopian tube on the side of the egg.Sperm attacked by Leukocytes (white blood cell army that is launched by the body's immunesystem).Remaining sperm must search for the doorway to the fallopian tube.
Implantation
Oh my, I am safe! I am going to live!!!
Approximately 10-30 sperm remain. Once inside, sperm are safe from attack by Leukocytes.Sperm are provided with nourishment from the Fallopian tube (ph levels, ion concentration stabilize) so they may stay alive for several hours, even days!
We have got to keep walking to find the egg!
This is too much. Where is this egg? Why this long tunnel?
The remaining sperm must attempt to find the egg at the upper end of the fallopian tube. Eggreleases chemicals that sperm can sense and they begin tomove more quickly.Egg (Ova): largest cell in the human body, only lives for 24 hours once it is released into the fallopian tube.
The zygote (union of sperm and egg) travels down the fallopian tubes towards the uterus, cellsbegin dividing. On day four the tiny bundle of cells is named a blastocyst.5 days later, the embryo breaks out of protective shell and implants in the wall of the uterus andbegins growing.
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