Not well. I've been fatigued all week and red spots have been showing up on my skin again.
That's not good. Sounds like your ALL is coming back
Doctors take a type of white blood cell from your body and genetically change the cells in a lab so they can better find your cancer.𝛀
I figured. I don't want to go through chemo again. It was draining experience for me. I read online about CAR T-Cell therapy. Can you tell me about that?
Yea I can. CAR T therapy has become really popular lately.
CAR T therapy is a kind of cancer treatment that uses cells from your own immune system.𝛀
CAR T stands for Chimeric antigen receptor T-cell𝛀
Then millions of these target-seeking cells are put back into your body.𝛀
CAR T-cell therapy may work when other treatments haven’t.↻
Sounds pretty good to me so far.
Don't forget though,the treatment is fairly new so doctors don't know how well it works or how long it lasts.
Unlike chemo and radiation, which kill healthy cells as well as cancerous ones, CAR T targets the tumors with more precision.
Also, CAR T-cell therapy is a one-time treatment, but it costs hundreds of thousands of dollars. And when you add in related costs, like hospital stays and home health care, the total may be closer to $1.5 million.
Jeez,I definitely don't have that much money. I'll have to talk to my insurance
That's the thing, the price is so high some insurance companies haven't figured out how to pay for it yet.
60% is bigger than 40% but I don't really like those odds.
Yea they aren't the best but,In some studies, 9 out of 10 people with acute lymphoblastic leukemia (ALL) whose cancer didn't respond to other treatments or whose cancer came back had full remission with CAR T-cell therapy.
More than half the children went on to receive a potentially curative stem-cell transplant, and approximately 60% of those children were still alive 5 years later without their cancer coming back or the children experiencing any disease-related problems.𝜴
I'm gonna have to start a gofundme because this is a lot. Tell me some pros, I need to know if this is worth the effort.
HAHA. Sure thing. An NCI-led research team, recently reported on long-term follow-up from children with relapsed ALL who had been treated with CAR T cells as part of a clinical trial.𝜴
Those are much better odds. I feel much better about it now. But still I ask what are the cons?
I'll tell you a few side effects. One is cytokine release syndrome (CRS). This happens when CAR T-cells begin attacking cancer and trigger an immune response in your body.
For some people, CRS may feel like a bad case of flu. In others, it can cause very low blood pressure, high fevers, and trouble breathing.
There are also brain and nervous system problems. These usually happen in the first 2 months after your infusion.
The most common ones are headache and feeling anxious. You might also be confused, have seizures, or not be able to talk at all for a few days. Most of these go away, but they can be life-threatening for some people.
Does It get worse than what you've already told me because this seems pretty risky?
Worse is debatable but I will tell you that you could get a new type of cancer after CAR T, or your ALL might come back. You should have your doctors watch for signs of cancer for the rest of your life.
CAR T can also kill off B cells, another kind of white blood cell you need to fight germs and foreign invaders, so you're more likely to get sick. Also, if you had hepatitis B before, it could start up again.
This is all a lot of information to take in. I need to sleep on it.
It is indeed a lot to take in. This is life changing treatment, it could be in a good way or a bad way. You have to decide if you want to take that risk. And don't forget to check in with your insurance.