Severe Combined Immunodefiency

Severe Combined Immunodefiency

Storyboard Text

  • Good morning class. Today I will tell you a story of a child who had severe combined immunodeficiency. Warning: many of you will cry.
  • If you do you are out of my class!
  • Secret gene mutation happening. Doctor doesn't know
  • Your son is going to be very healthy
  • 5 years later
  • I don't know son, we will take you to the doctor to get all better.
  • Why am I always sick mom
  • The next day
  • What are his symptoms?
  • I dont understand why my son is always sick
  • He is having severe difficulty breathing, diarrhea and it looks to me like he is not growing
  • I'd like to perform some tests on him. Bring him in tomorrow
  • The next day
  • Ok just make me better
  • Son, I am a doctor and I would like to perform some tests on you
  • Why is this happening to him
  • OH, sorry. There is some mutation in the x- gene so only the boys have a chance of getting it as the girls are carriers
  • This is an x-linked recessive trait, so its your fault he has it
  • After the tests were done
  • Can I do anything to help him
  • Whats the verdict doctor, why is he always sick?
  • I'm sorry to say this. But your son has SCID
  • Usually for newborns we test them with the IDF screening initiative, but your son didn't go through with that when he was born, so we are too late to cure it but there are treatments
  • Do you want to take that risk?
  • But there is a risk if it doesn't work. It could either kill him right there and then. Or he would eventually die as his immune system won't be able to handle the outside
  • Yes
  • You can help by being a donor for a bone marrow transplant. If we do the transplant, there is a high chance he won't get sick as often anymore.
  • I love you. You will be alright
  • Im sorry, your bone marrow wasn't compatible with his. Enjoy your time with him. He will be gone in 3 days
  • oh god
  • After the surgery
  • He is dying due to the common cold
  • Day 1
  • He needs to be put in a safety bubble
  • I love you mom
  • I iii llllovvve yyyou ttooo
  • Day 2
  • Day 3
  • I love you mother
  • Thats all folks thank you for listening. Roger, out of my class
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