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- Hmm. I think I will begin my experiment by dripping reagents onto lung tissue samples and see what this can accomplish.
- Early 1880s- Hans Christian Gram
- Whoah! The bacteria changed color, differentiating this bacteria into Streptococcus pneumoniae and Klebsiella pneumoniae due to differences in the cell wall.
- I have determined that bacteria that appear purple or brown, with cell walls composed of peptidoglycan are “gram-positive” while the red bacteria without cell-walls will be “gram-negative”.
- While I have published the method and am confident in its effectiveness, I would like to point out that it is still quite imperfect and defective.
- As the associate professor of medicine at Harvard Medical School, I would like to announce that “the Gram-stained smear” should, in fact, be used in physical examinations of patients with acute bacterial infections.
- 1974- Pierce Gardner
- We also recommend all physicians delivering primary care in acutely ill patients add the technique to their repertoire.
- New tests have emerged due to the errors with the Gram staining technique, yet it is a quite commonly performed test in the clinical microbiology laboratory, in addition to foundational technique in treating bacterial infections and saving lives
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