M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells
M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells
M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells
M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells
M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells
M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells
M2 macrophages trigger differentiation of Satellite cells into specialized daughter cells called myoblasts.
M2
Undoing the Damage: Anti-inflammatory response
Negative feedback system
Stimulus : Cytokines released by M1 Macrophages
Sensor: Nerve cells in the skin brain
Control : White blood cells (Monocytes)
Organ systems involved :lymphatic, musculoskeletal, nervous system
Effector: M2 Macrophages
Myoblasts fuse with other myoblasts and/or damaged muscle fibre to reconstruct damaged muscle tissue.
nom nom
Specialized proteins that help gene expression, aka transcription factors, MyoD and Myf5 activate to prepare for cell fusion.
MyoD
Myf5
M2 macrophages activate and counter inflammation created by M1 macrophages. The M1 macrophage population declines.
M2
Undoing the Damage: Repairing Muscle Fibre
Negative feedback system
Stimulus : M2 Macrophage
Sensor: Nerve cells in the skin brain
Organ systems involved :lymphatic, musculoskeletal, nervous system
Control: Satellite Cells
Effector: Satellite Cells